WELCOME TO THE 
(RESOURCE) LIBRARY

SUPPORT FOR YOU AND YOUR PRACTICE IS JUST A CLICK AWAY

Several resources are available to help you prescribe and access LIVMARLI for your patients. Patient-friendly resources and videos are also available to share and discuss with your patients.

Real People Taking LIVMARLI

Hear from real patients and their families as they share their unique experiences—life before diagnosis, challenges before starting LIVMARLI, and the difference LIVMARLI is making in their lives.*

Meet Finley

Finley experienced multiple symptoms for months before finally getting diagnosed and starting on LIVMARLI.

Meet Finley: 1 year old
Meet Téa

Téa struggled with persistent itching and disrupted sleep until she started LIVMARLI.

Meet Téa: 8 years old
Meet Tyler

Tyler spent the first 10 years of his life battling constant itching and relying on ineffective treatments before finally finding relief.

Meet Tyler: 11 years old

*Not all patients taking LIVMARLI will have the same experiences.

Patient and Doctor Dialogue

Explore the patient experience through the eyes of an 8-year-old. Téa, currently taking LIVMARLI, chats with her beloved physician, Dr. Bass, about life with Alagille syndrome and shares how doctors can better help patients like her.

Patient and Doctor Dialogue
Kids on bike

LIVMARLI Resources for You

LIVMARLI Brochure
LIVMARLI Brochure
LIVMARLI Brochure

Learn more about LIVMARLI and how it may help appropriate patients.

Download PDF

Real-World Patient Profiles Brochure
Real-World Patient Profiles Brochure
Real-World Patient Profiles Brochure

Take a closer look at who may be appropriate for LIVMARLI.

Download PDF

Mirum Access Plus Resources for You

Patient Enrollment Form
Patient Enrollment Form

Download and fax this form to Mirum Access Plus to prescribe LIVMARLI and/or enroll your patients for support.

Download PDF |
How to Fill Out the Patient Enrollment Form

Rx to Fill Guide
Rx to Fill Guide

Refer to this step-by-step guide for more information on prescribing LIVMARLI.

Download PDF

Template Letter of Medical Necessity
Template Letter of Medical Necessity

Download and use this template letter to support the payer approval process with insurance plans.

Download PDF  |
How to Fill Out the Letter of Medical Necessity

Prior Authorization Checklist
Prior Authorization Checklist

Review the supporting clinical documentation that may be required by a patient’s insurance plan.

Download PDF

Tips for Payer Approval
Tips for Payer Approval

Keep these tips and questions in mind to help with prior authorizations (PAs) and appeals for your patients.

Download PDF - PA Tips

Download PDF - Appeals Tips

Mirum Access Plus Mobile
Mirum Access Plus Mobile

Consider this digital option to enroll your patients in Mirum Access Plus support, easily provide their insurance information, and eSign documents to expedite processing.

Get Patients Started

Additional Resources for You

Itch Severity Tool
Itch Severity Tool
Itch Severity Tool

Learn how you can use clinically validated tools to rate itch severity over time.

Download PDF

LIVMARLI Resources for Patients and Caregivers

Patient Website
Patient Website

Share this website with your patients to explain LIVMARLI treatment in a patient-friendly manner.

Visit Patient Website

Patient Brochure
Patient Brochure

Provide this resource to your patients considering or receiving LIVMARLI treatment.

Download: English  |  Español

Quick Look Brochure
Quick Look Brochure

Provide this resource to caregivers looking for a summary of information about LIVMARLI.

Download PDF

Discussion Guide
Discussion Guide

A short, simple list of questions to help your patients discuss LIVMARLI with you and gain more knowledge about and confidence in getting started.

Download: English  |  Español

Teen Brochure
Teen Brochure

Offer this guide to teenagers who are ready to take charge of their treatment.

Download PDF

Mirum Access Plus Resources for Patients and Caregivers

Steps to Getting Medication
Steps to Getting Medication
Steps to Getting Medication

This resource helps explain to your patients the initial process of receiving LIVMARLI prescription and treatment.

Download: English  |  Español

Mirum Access Plus Brochure
Mirum Access Plus Brochure
Mirum Access Plus Brochure

This brochure summarizes the Mirum Access Plus support available to your patients.

Download: English  |  Español

Patient Consent Form
Patient Consent Form
Patient Consent Form

Patients can enroll in the support program by texting ENROLL to 1-833-MAP-4YOU
(1-833-627-4968). Or, they can download and sign the Patient Consent Form to sign up.

Download: English  |  Español

Mirum Access Plus Mobile
Mirum Access Plus Mobile
Mirum Access Plus Mobile

Encourage patients to visit the Patient Website to sign up for Mirum Access Plus support through their mobile phones.

Get Patients Started

Additional Resources for Patients and Caregivers

LIVMARLI Peer Program
LIVMARLI Peer Program
LIVMARLI Peer Program

Patients and caregivers can chat with LIVMARLI peers—parents and caregivers who know what it’s like to navigate life with Alagille syndrome. Connect with other families who understand and receive resources and updates.

Download PDF  |  Visit Peer Program Website

Teddy Activity Book
Teddy Activity Book
Teddy Activity Book

An educational children’s book about Alagille syndrome that can help patients understand the disease through storytelling and engaging activities.

Download PDF

Itch✓™ App
Itch✓™ App
Itch✓ App

Itch✓ is an app that makes it simple for patients and caregivers to track symptom patterns over time. The app generates customized reports to share at appointments. 

Download on the Apple App Store®  |
Get it on Google Play

Itch✓ Printable Journal
Itch✓ Printable Journal
Itch✓ Printable Journal

Patients and caregivers without a smartphone can still bring a detailed symptom journal to their next appointment with the Itch✓ Printable Journal.

Download: English  |  Español

Apple®, iPhone®, App Store®, and the Apple Logo are trademarks of Apple Inc.

Android is a trademark of Google LLC.

Survey the
Battlefield

Battle the bile monster with LIVMARLI—learn how to help keep itch at bay for your patients with Alagille syndrome.

See How LIVMARLI Works

Encourage patients to download the Itch✓ app to help them track symptom patterns over time and generate customized reports to share at appointments.

Check Out the Itch✓ App

Mirum Access Plus assists both you and your patients at every turn, helping you navigate the payer approval process—and beyond—with ease.

Learn More About
Mirum Access Plus
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Important Safety Information

Warnings and Precautions

Liver Test Abnormalities: Patients enrolled in clinical trials had abnormal liver tests at baseline. In the main clinical trial, treatment-emergent elevations or worsening of liver tests (ALT, AST or T/DB) relative to baseline were observed. Obtain baseline liver tests and monitor during treatment. Dose reduction or treatment interruption may be considered if abnormalities occur in the absence of other causes. For persistent or recurrent liver test abnormalities, consider treatment discontinuation. Discontinue permanently if a patient progresses to portal hypertension or experiences a hepatic decompensation event.

GI Adverse Reactions: Diarrhea, abdominal pain and vomiting were reported as the most common adverse reactions. If diarrhea, abdominal pain and/or vomiting occur and no other etiologies are found, consider reducing the dose or interrupting LIVMARLI. For diarrhea or vomiting, monitor for dehydration and treat promptly. Consider interrupting LIVMARLI dosing if a patient experiences persistent diarrhea or has diarrhea with accompanying signs and symptoms such as bloody stool, vomiting, dehydration requiring treatment, or fever. Restart LIVMARLI at 190 mcg/kg/day when diarrhea, abdominal pain or vomiting resolve, and increase the dose as tolerated. If they recur upon re-challenge, consider stopping LIVMARLI treatment.

Fat-Soluble Vitamin Deficiency: ALGS patients can have fat-soluble vitamin (FSV) deficiency (vitamins A, D, E, and K) at baseline, and LIVMARLI may affect absorption of FSV. In the main clinical trial, treatment emergent FSV deficiency was reported in 3 (10%) patients during 48 weeks of treatment. Obtain baseline serum levels and monitor during treatment, along with any clinical manifestations. Supplement if deficiency is observed. Consider discontinuing LIVMARLI if FSV deficiency persists or worsens despite adequate FSV supplementation.

Adverse Reactions

The most common adverse reactions (≥5%) are diarrhea, abdominal pain, vomiting, fat-soluble vitamin deficiency, liver test abnormalities, gastrointestinal bleeding and bone fractures.

Drug Interactions

Administer bile acid binding resins at least 4 hours before or 4 hours after administration of LIVMARLI.

A decrease in the absorption of OATP2B1 substrates (eg, statins) due to OATP2B1 inhibition by LIVMARLI in the GI tract cannot be ruled out. Consider monitoring the drug effects of OATP2B1 substrates as needed.

Dosing Information

LIVMARLI should be taken 30 minutes before a meal in the morning. The provided oral dosing dispenser must be used to accurately measure the dose. Any remaining LIVMARLI should be discarded 100 days after first opening the bottle.

Please see full Prescribing Information for LIVMARLI.